John Sidney Blyth Barrymore , was an American actor, frequently called the greatest of his generation. He first gained fame as a stage actor, lauded for his portrayals of Hamlet and Richard III. His success continued with motion pictures in both the silent and sound eras. His classic nose and distinguished features won him the nickname "The Great Profile".

A member of a multi-generation theatrical dynasty, he was the brother of Lionel Barrymore and Ethel Barrymore, and the grandfather of Drew Barrymore.