“Don't challenge resistance. Don't resist challenge.”
Sim Stevenz
“Again and again I am brought up against it, and again and again I resist it: I don't want to believe it, even though it is almost palpable: the vast majority lack an intellectual conscience; indeed, it often seems to me that to demand such a thing is to be in the most populous cities as solitary as in the desert.”
Friedrich Nietzsche
“Many more of the infections we see are caused by the resistant bacteria. The bacteria has developed resistance to some of the antibiotics that used to easily cure the infections.”
Margaret Spear
“HIV presents special therapeutic challenges to the drug development team, including resistance, complex pharmacokinetics, and patient compliance. Our modeling and simulation approach in HIV, as in other therapeutic domains, is to integrate relevant sub-models, estimate key parameters from trial data, and simulate candidate trial designs. The business benefits can include optimizing the design of the next trial or sequence of trials, better go/no-go decisions, and strategies to optimize unavoidable tradeoffs such as that between patient compliance and difficult dosing.”
Shawn O'Connor
“If someone slaps you on one cheek, offer the other cheek also...but of course if you were able to stand soberly after the first slap.”
Toba Beta
“The repression of all those daring to resist the autocratic regime represents a severe challenge to the restoration of democracy in Nepal.”
Warren Christopher
“As the Sandwich-Islander believes that the strength and valor of the enemy he kills passes into himself, so we gain the strength of the temptations we resist”
Ralph Waldo Emerson
