“How does the primary tumor cause the bone marrow cells to settle somewhere and provide a fertile field for metastasis - does it send out chemicals that stimulate the bone marrow cells? And why do those bone marrow cells settle where they do? It also opens possibilities for other avenues of attack against the cancer to prevent its spread. Before anything else, however, other researchers need to confirm that these findings are true.”
Tom Tucker
“Selective electrochemical tumor ablation can be performed on an outpatient basis and provides a relatively non-invasive and well-tolerated therapeutic option for patients with troublesome cutaneous and subcutaneous melanoma metastases.”
John Thompson
“One of the potential uses we envision is to use the ART treatment as a way to use tumor components to immunize cancer patients against their own cancer cells. The current problem with this treatment strategy is that the tumor gives off a variety of soluble products which we don't fully understand, but which we know wreck havoc on the immune system by suppressing its various components. If we can use the ART drugs to increase the number of newly produced T cells in cancer patients first, we can potentially improve the likelihood of getting a cancer vaccine to work.”
David McKean
“One of the potential uses we envision is to use the ART treatment as a way to use tumor components to immunize cancer patients against their own cancer cells, ... The current problem with this treatment strategy is that the tumor gives off a variety of soluble products which we don't fully understand, but which we know wreck havoc on the immune system by suppressing its various components. If we can use the ART drugs to increase the number of newly produced T cells in cancer patients first, we can potentially improve the likelihood of getting a cancer vaccine to work.”
“Small molecules penetrate the tumor very efficiently, but are also removed very efficiently. Larger molecules penetrate more slowly, but they stay in the tissue longer, giving the patient a greater concentration of the drug. If you balance the two factors with a precise weight, you get optimal drug concentration.”
Ashutosh Chilkoti
“Currently, there is no way of knowing the exact dose of radiation received by a tumor. And, because most organs shift inside the body depending on whether a patient is sitting or lying down, for example, the tumor also shifts. This technology will allow doctors to pinpoint the exact position of the tumor to more effectively administer radiation treatments.”
Babak Ziaie
“It decreases the production of estrogen which we think feeds the tumor.”
Dr. Merla Puray
