“Eventually, I'd like to get into therapeutic riding. Next year, I'm going to Colorado for 10 days for the John Lyons training certification. It's not something I have to do, but I really want to for my own benefit.”
“What can be said in New Year rhymes,
That's not been said a thousand times?
The new years come, the old years go,
We know we dream, we dream we know.
We rise up laughing with the light,
We lie down weeping with the night.
We hug the world until it stings,
We curse it then and sigh for wings.
We live, we love, we woo, we wed,
We wreathe our prides, we sheet our dead.
We laugh, we weep, we hope, we fear,
And that's the burden of a year.”
“HIV presents special therapeutic challenges to the drug development team, including resistance, complex pharmacokinetics, and patient compliance. Our modeling and simulation approach in HIV, as in other therapeutic domains, is to integrate relevant sub-models, estimate key parameters from trial data, and simulate candidate trial designs. The business benefits can include optimizing the design of the next trial or sequence of trials, better go/no-go decisions, and strategies to optimize unavoidable tradeoffs such as that between patient compliance and difficult dosing.”